Plus, how AI is upending scientific discovery.

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Hey readers,

Marina here. 

 

What can an economist teach us about misery? 

 

I had that question in mind while reading the new book The Opposite of Happiness: How Bad Feelings Make and Break Us, by eminent researcher George Loewenstein. The field is not exactly known for its facility with human emotions, but Loewenstein is a co-founder of behavioral economics, the subdiscipline that studies the many ways that people depart from the ideal of the perfectly rational actor. He’s spent his career investigating how psychology and emotion shape our judgments, and his latest book offers a sweeping account of how suffering structures human life. 

 

That might sound very bleak, like the opposite of a fun read. But the book itself isn’t distressing — it’s a bracing, useful, and even comforting lens on what it means to be alive. It emerged from a period of profound suffering in his own life, one where, he writes, he “thought about suicide constantly.” Writing it, he told me in a recent interview, was “kind of a silver lining for my own misery.” 

 

In Loewenstein’s own words, The Opposite of Happiness is not a self-help book. To him, understanding is its own reward. Though he adamantly refuses to dispense life advice, I still think the book offers much that can help us live more wisely, a little less at war with our emotions.

 

“Misery is inescapable,” Loewenstein writes. “It’s not some malfunction or a bug in the system. It is the system.” Negative emotions are “more powerful, persistent, and pervasive than positive ones.” That is because, he argues, unpleasant feelings — hunger, pain, anger, loneliness — are how evolution motivated us to do the things we need to survive and pass on our genes. They still dominate our conscious experience, however mismatched they may feel to our modern circumstances. 

 

Some version of that insight, that dissatisfaction is woven into the human condition, has been known to humans for eons, of course, captured in philosophical teachings like Buddhism’s Four Noble Truths. The father of economics himself observed that people work hard to earn riches, only to discover the result offers no lasting contentment. “It is this deception which rouses and keeps in continual motion the industry of mankind,” Adam Smith wrote in The Theory of Moral Sentiments. “It is this which first prompted them to cultivate the ground, to build houses, to found cities and commonwealths, and to invent and improve all the sciences and arts.” 

Loewenstein puts this understanding into the language of modern psychology, speaking to a current of anxiety and unhappiness running through American life today. It also points to enduring questions about what the purpose of human progress and prosperity is, anyway. 

 

Many of us could particularly benefit from the concept of negative “meta-emotions,” or the judgmental feelings we have about our negative feelings. “At the heart of so many of our miseries is not the fact that we feel bad, but the belief that we should feel otherwise,” he writes.  That line immediately rang true to me — merely acknowledging to myself that it’s not a big deal if I feel terrible from work stress, or my cat’s deteriorating health, or whatever else happens to be weighing on me, helps to lighten the load. What if we really tried to wryly embrace the reality that it’s extremely normal for life to suck sometimes? The reward might not be happiness, exactly — an elusive and poorly understood state anyway, Loewenstein points out — but a little less misery.  

 

I recently spoke with Loewenstein about his book — he had a gentle, faintly melancholic air, and took a surprisingly generous interest in some of the choices I was weighing in my own life. Part of our conversation, condensed and edited for clarity, is below. 

 

Americans seem pretty unhappy right now. There has been endless discourse about that. Do you think that your book adds something to that conversation?

 

I do — I was just an expert on the Meta case that recently settled. I was an expert on the side that was against Meta. I think one of the causes of declining mental health is, in fact, social media. It really exacerbates the types of social comparisons that lead to envy and loss of self-esteem. I would like to think that I provide some new insights into how these modern technologies help to exacerbate the mental health crisis. 

 

One analysis of that, based on what I've learned from your book, might be: We as humans are so guided by negative emotions, and often those emotions are relational in nature and have to do with how we compare to other people.  Social media is then quite naturally going to tap into and amplifying negative emotions that we’re easily manipulated by.

 

That’s right. I think of it in two ways. One is there's kind of a mismatch between the circumstances in which we evolved and the modern environment. And the other is that in the capitalist economy, there are, especially in the internet age, all these entities that are trying to exploit our evolutionary programming for their own good and not for our good. 

 

The premise of the book, as you write, is that “misery is inescapable. It’s not some malfunction or a bug in the system. It is the system” — it’s like our default state. Can you unpack what that means? 

 

I agree with everything you said until “default.” Different people have different set points, and there are some happy people around. I happen to be a glass-half-empty person. My natural state is a little bit below zero. But there are very few people who don't experience some form of misery frequently and intensely. 

 

The evolutionary function of most negative emotions is pretty obvious, whereas the evolutionary function of happiness is sort of murky. And misery is so dominant that all it takes is a little bit of misery, a little bit of negative emotion, to wipe out any positive emotion. You go out to a really nice dinner at a fancy restaurant with your significant other, and you say something thoughtless and they get offended or they say something thoughtless and you get offended. All of a sudden you can't even taste the food or appreciate the beautiful surroundings. 

 

Paul Rozin at the University of Pennsylvania referred to this as the “roach effect”: If you drop a roach into a vat of fine French wine, you don't want to drink the wine. But if you take a roach, you can add as much wine as you want to it and you're not going to want to eat the roach.

 

One of the strongest positive emotions is relief — which is interesting and not a coincidence, because it's relief from negative emotions. It’s telling that maybe the strongest positive emotion involves the elimination of negative emotions.

 

You can think of misery as a stick trying to get you to do things that evolution thought were good for you; the stick is very immediate, and you know exactly what it's telling you. If you are hungry, it's time to eat. If you’re in pain, you’re injured, you’ve got to do something about it. But the carrot is different. The carrot, which is positive emotions, you have to think ahead, Oh, if I did this, then I would experience this positive emotion. It requires a kind of second-order thinking, whereas misery is just immediate. Evolution figured out probably very rapidly, probably when we were single-cell protozoa or something, that sticks are a way better way to get an organism to do what it needs to do than carrots.

 

How confident are you that the evidence base we have about the psychology of negative emotions generalizes to humanity as a whole and that it's not culturally biased?

 

Emotion researchers have looked across cultures, and they tend to observe the same basic emotions in a very, very wide range of cultures. What does vary across cultures is what induces the emotions. For example, shame — something that we would be unashamed of, somebody in a different country might be very ashamed of, and vice versa. A lot of these emotions are self-conscious emotions. They have to do with how we interpret the world and whether we’re living up to some kind of standard. Often we get it from culture, from religion, things like that. But I think the emotions themselves are not universal, but pretty close to universal. My guess is that all 12 negative emotions that I write about are manifested in pretty much all different cultures, from those that have very little connection to Western civilization to advanced economies. 

 

Another timely thread that your book is in conversation with is this idea that American culture has become intolerant of ordinary negative emotions in a way that's maladaptive. Suzanne O’Sullivan’s recent book The Age of Diagnosis, for example, covered our obsession with medical labels and how they might make us prone to thinking that feeling bad means that there's something medically wrong with us. What do you think about that? Have we gotten bad at feeling bad?

 

It is striking to me how it seems like all the young people I meet talk about their therapist, and a lot of them talk about the drugs that they take. Young people also talk about anxiety and depression almost like one word, “anxiety-and-depression.” In my generation, anxiety and depression were two entirely different things. 

 

I think it’s good that younger generations are more comfortable talking about these things and getting help. I do worry that it can be, to some degree, pathologizing. There's an awful lot of self-focus there. And I kind of worry that if you are dealing with your mental health problems by taking drugs, that it reduces your motivation to figure out things like how to reorganize your life to feel better. But I don’t want to sound too much like a dinosaur.

READ THE REST OF THE INTERVIEW ON VOX

Marina Bolotnikova

Senior reporter

Marina Bolotnikova

Senior reporter

 
 

CAN'T STOP THINKING ABOUT...

with Ananya Rupanagunta

 

Title: Future Perfect fellow
What I cover: Climate and population health, but really how the humans are changing the way we live
What I'm rereading: Abraham Verghese’s The Covenant of Water

What is science? When most of us try to answer that question, we tend to think first of scientists: that tweedy professor feverishly scrawling equations across a blackboard in chalk or the white-coated technicians in a lab discovering a promising new combination of genes after decades of experimentation. Increasingly, however, that’s the work being done by (or at least with the support of) artificial intelligence. In that sense, large language models seem to be displacing humans from the work of science. I think there’s some truth to that, but if we really want to understand how AI is changing science, we have to look to a much older definition of science itself. 

In the 16th and 17th centuries, Enlightenment thinkers significantly shifted the way we thought about and studied the natural world. In 1620, Francis Bacon, lord chancellor of England, established empirical observations and inductive reasoning as the primary methods of natural philosophy. 

These values, which would come to differentiate science from mysticism, were fundamentally technological. Bacon’s key book is titled Novum Organum, or “new instrument,” because in order to study the natural world, we must be able to measure it through instruments and tools. In this sense, an AI enthusiast might reasonably interject that AI is just another highly powered processing tool for the data we collect, perhaps the most advanced organum we have created. 

The trouble is that the “black-box” nature of these models actually inverts the very purpose of a scientific instrument, which is to help us understand what we are seeing when we are unable to see it with our own eyes. Science, in the Baconian definition, isn’t the practice of taking the world’s measure: It’s the project of making the world intelligible, and measurement is a means to achieve understanding. AI may be undermining that through the very power of the tools it offers us, if we don’t find a way to elucidate what is happening in the model’s hidden layers first. Indeed, the opacity of LLMs also threatens scientific replicability — the possibility of recreating another scholar’s experiments or equations to validate their conclusions. Replicability is not just important to support theory, but to also ensure the accuracy of scientific claims that may significantly challenge the field, or even the safety of next generation drugs that promise to transform medical care. 

I’m reminded of an observation from another great Enlightenment intellectual, John Locke: "No man’s knowledge here can go beyond his experience,” he wrote in An Essay Concerning Human Understanding (1689). Can we really trust the knowledge autonomous science generates for us when we don’t really understand the stream of thought that brought it into being, or experience the process of discovery ourselves? Can we even say that that is science?

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THE BIG STORY âž 

The cruelty of a beloved American pastime

The humane myth of catch and release fishing.

Catch a fish. Let it go. A far more humane option than keeping it for dinner, right? As Vox’s Future Perfect senior reporter Kenny Torrella shows in his latest article, this may not necessarily be the case. 

Millions of Americans enjoy fishing, and in recent decades an increasing proportion of lines are cast just for catch and release, which sounds like progress. But even as a kid, trying to pull out a hook that had gotten lodged in a small perch’s eyeball so that I could toss her back into a murky pond, I wondered, is this a good idea? 

Since then, a growing body of research has been probing what fish feel. Do they have the capacity to experience pain as we (or other mammals) might? What are their odds of survival after, for example, a 10-year-old clumsily dislodges a hook from their face and throws them back into their watery world full of predators and disease…and more hooks dangled by more anglers? In his thought-provoking piece, Kenny dives into this science and talks with researchers of all stripes — including those who fish, too — to better understand the ethics of catch and release fishing. —Katherine Courage, deputy editor Future Perfect

READ THE STORY
 
 
 

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